EBV INFECTION OF PRIMARY COLONIC EPITHELIAL CELLS CAUSES INFLAMMATION, DDR AND AUTOPHAGY DYSREGULATION, EFFECTS THAT MAY PREDISPOSE TO IBD AND CARCINOGENESIS

EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis

EBV is a gammaherpesvirus strongly associated to human cancer.The virus has been shown to play a role also in inflammatory diseases, including IBD, Cigarette Lighter Power Adaptor in the context of which colon cancer more frequently arise.In this study, we show for the first time that EBV infects primary colonic epithelial cells (HCoEpC), promotes

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Comparison of typical and atypical computed tomography patterns regarding reversibility and fibrosis in pulmonary sarcoidosis

PURPOSE: This study aims to investigate whether there is a significant difference between typical and atypical parenchymal patterns in the development of fibrosis, which is the most crucial factor affecting morbidity in pulmonary sarcoidosis.METHODS: In our hospital, 145 cases with Siltzbach Types 2 and 3 sarcoidoses diagnosed by clinical, radiolog

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